![]() Throughout the four novels and 56 short stories featuring Holmes, a number of characters recur, including the bumbling Scotland Yard inspector Lestrade the group of “street Arabs” known as the Baker Street Irregulars, who are routinely employed by Holmes as informers his even wiser but less ambitious brother, Mycroft and, most notably, his formidable opponent, Professor James Moriarty, whom Holmes considers the “Napoleon of crime.”Ĭlaiming that Holmes distracted him “from better things,” Conan Doyle famously in 1893 (“ The Final Problem”) attempted to kill him off during a violent struggle on Switzerland’s Reichenbach Falls, both Holmes and his nemesis, Professor Moriarty, are plunged over the edge of the precipice. ![]() Holmes appears to undergo bouts of mania and depression, the latter of which are accompanied by pipe smoking, violin playing, and cocaine use. His London abode at 221B, Baker Street, is tended by his housekeeper, Mrs. Watson’s narrations describe Holmes as a very complex and moody character who, although of strict habit, is considerably untidy. What is the name of the schoolteacher in "The Legend of Sleepy Hollow"? Where does Sherlock Holmes live? Test your knowledge in this quiz of Captain Nemo, Rip Van Winkle, and other literary characters. SpaceNext50 Britannica presents SpaceNext50, From the race to the Moon to space stewardship, we explore a wide range of subjects that feed our curiosity about space!.Learn about the major environmental problems facing our planet and what can be done about them! Saving Earth Britannica Presents Earth’s To-Do List for the 21st Century.Britannica Beyond We’ve created a new place where questions are at the center of learning.100 Women Britannica celebrates the centennial of the Nineteenth Amendment, highlighting suffragists and history-making politicians.COVID-19 Portal While this global health crisis continues to evolve, it can be useful to look to past pandemics to better understand how to respond today.Student Portal Britannica is the ultimate student resource for key school subjects like history, government, literature, and more.This Time in History In these videos, find out what happened this month (or any month!) in history.#WTFact Videos In #WTFact Britannica shares some of the most bizarre facts we can find.Demystified Videos In Demystified, Britannica has all the answers to your burning questions.Britannica Explains In these videos, Britannica explains a variety of topics and answers frequently asked questions.Britannica Classics Check out these retro videos from Encyclopedia Britannica’s archives. ![]()
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![]() ![]() The issue caused the person making the call to sound quiet or far away when speaking, making them difficult to hear. The CarPlay bug caused iPhone 14 Pro and Pro Max users to experience low volume levels when attempting to make a hands-free phone call in a vehicle. ![]() Mail crashes on launch after receiving a malformed email Camera may be slow to launch or switch between modes on iPhone 14 Pro and iPhone 14 Pro Max Low microphone volume can occur during CarPlay phone calls on iPhone 14 models Incoming call and app notifications may be delayed or not delivered on iPhone 14 Pro and iPhone 14 Pro Max This update provides bug fixes and important security updates for your iPhone including the following: The iOS 16.0.3 update can be downloaded on eligible iPhones over-the-air by going to Settings > General > Software Update.Īccording to Apple's release notes, the iOS 16.0.3 update addresses a number of bugs that iPhone users have run into over the course of the last few weeks. The iOS 16.0.3 update follows iOS 16.0.2, software that addressed a number of launch day bugs on the iPhone 14 models. MacOS Ventura will also be released in October - potentially alongside iPadOS 16.1.Īpple today released iOS 16.0.3, a minor bug fix update that comes a few weeks after the launch of the iOS 16 operating system. Apple also delayed external display support for iPad models with the M1 chip until later this year.Īpple has improved Stage Manager in recent weeks, but some users said the feature still has several issues in the latest iPadOS 16 beta. IPadOS 16 was initially expected to be released alongside iOS 16 in September, but Apple delayed the update after some users criticized the new Stage Manager feature that allows for multiple apps to be used in overlapping windows.Īpple recently expanded Stage Manager to older iPad Pro models with A12X and A12Z chips released in 20, albeit without external display support, which limits the feature to four apps on the built-in display on these models. Apple has historically held launches the week of its earnings calls in October.Īpple previously said iPadOS 16 would be released in October, but the company did not provide a specific release date. And if you have added multiple Lock Screens, you can customize the clock style for all of them.IPadOS 16.1 is on track to be released the week of Oct. To make further revisions, follow the same steps mentioned above. You have successfully changed the color, font, and style of the clock on your iPhone Lock Screen. Note: The color you pick for your clock will also apply to the day, month, and date indicator that sits above the time.Ħ) With everything done, tap X > Done > Set as Wallpaper Pair. It will recognize that color and set it as the clock color. Tap its icon from the top left and then drag its selector over a part of your wallpaper. One super useful tool here is the color picker. From here, you can use the various options to set the perfect color you want. ![]() To choose from millions of colors, swipe left to the end and tap the last dot. But you can use a different shade by selecting the desired colored dot and adjusting its saturation using the slider. ![]() Your iPhone takes into account the appearance of your wallpaper and automatically sets the clock’s look to a color it thinks is best. The font for the day, month, and date can’t be altered.ĥ) After you finish selecting the font type, we can move our attention to color. Note: You can only adjust the clock’s font. For example, you can choose from Arabic (most common around the world), Arabic Indic (used in the regions east of the Arab world like Egypt, UAE, Oman, etc.), or Devanagari (meaning divine city’s script, used in India and adjoining areas.) You can also tap the globe button to see fonts from different scripts. After that, tap and hold the Lock Screen to enter editing mode.ģ) Tap the clock area, and a Font & Color pane will slide up from the bottom of the screen. Customize how time and date look on your iPhone Lock Screenġ) Wake up your iPhone and make sure it’s unlocked. In this post, we will show you how to change the color, font, and even the script for the clock on the Lock Screen of your iPhone in iOS 16. Therefore, styling it with your favorite color and font will go a long way in personalizing your iPhone. You glance at the time, date, day, and month on the iPhone Lock Screen several times daily. ![]() ![]() ![]() What if it could be done automatically? Now you can. Think about how much time you spend managing your files, fiddling with their filenames to make them fit your personal taste. ![]() Keeping them tidy and organized is important so you can easily find what you are looking for. Use with multiple files and folders.Ĭlick here to Download Flash Renamer for free!Įverybody has a lot of files these days, be it digital photos, music, movies or documents. Quote: the most advanced batch file renamer utiltity. EXE - renames files quickly! Plus you can rename digital photo files generated by digital cameras with flash renamer. This portable freeware is also a powerful mp3 file renaming & management utility.įlash Renamer is a bulk rename utility. Learn how to manage your digital camera picture collection by clicking here. You can rename & manage your computer images. This is a program to rename multiple files! It's a powerful digital camera picture utility. Rename all files with ease - Perfect multiple file renamer for windows XP, Vista, 7 & 8.īest windows explorer replacement freeware For webmasters, a software for mass file management. Digital camera software for automation of monotonous work by hand. Works on windows 95 / 98 / me / nt / 2000 / xp / vista / 7 / 8. Tag & rename id3 your mp3 music files very fast.Ĭhange the name of many files & folders. Flashren is a file, mp3 and jpeg picture renamer. Here's a batch renaming software to manage the names, organize & tag your mp3 files! You can do sequential renaming: add counters and numbers to filenames. ![]() Rename files & images! It's a fast, easy & powerful batch/bulk renaming utility for files, photos & music/mp3. If you find yourself with a lot of files with cryptic names, for example photos from your digital camera, and you want to give them meaningful names, then a batch rename utility is your best friend!įlash Renamer is a tool for automated file renaming. Batch renaming can also be referred to as mass file renaming, rename en masse and bulk renaming. Spend your time doing something better!ĭownload today and discover how much time and effort you will save by letting Flash Renamer do the work for you!įlash Renamer is an awesome utility that really is the missing piece of Windows!īatch renaming means changing the names of a group of files in an automated fashion, to save time and reduce the amount of work involved.Right click context menus to quickly access FR when you need it.Oldest still developed batch rename program.Realtime preview shows changes before you actually rename.Extend with ExifTool for thousands of more properties and tags!.Extract media properties & metadata, such as width/height and duration.Create your own rename rules with scripting!.Supports mp3, ogg vorbis, wma, mp4, flac, mpc, spx, tta, wv and more!.With more features than any other program on the market and a critically acclaimed user interface, this is batch renaming at it's best! Since 1999 Flash Renamer has been the program of choice for users in need of a fast and intuitive way to rename multiple files in an automated fashion. ![]() ![]() ![]() Zeichner recommends moisturizing ingredients like shea butter, hyaluronic acid, and avocado oil.īelow, the peels and masks experts recommend. For those simply in need of a little extra hydration, Dr. "These help dissolve skin cells in the outer skin layer so that the outer, rough skin can shed,” he says. Zeichner says to look for ingredients like glycolic and lactic acid. : Soft Touch Foot Peel Mask - Pack of 2 Feet Peeling Masks for Dry, Cracked Heels & Calluses - Exfoliating Foot Mask Peel for Baby Soft Skin. FREE Delivery on your first order shipped by Amazon. ![]() There are peels that will literally exfoliate and dissolve dead skin cells on your feet to reveal smooth skin underneath and there are others that infuse moisture to make feet softer. FOLAI Foot File Foot Pedicure Tool, Stainless Steel Foot File, Dead Skin Remover Foot Care Pedicure Tool for Cracked Feet, Make Foot Beauty and Extra Smooth (Black) 5,830. Meet our expert: Joshua Zeichner, MD, associate professor of dermatology at Mount Sinai Hospital in New York City 100 Amazon 1-1/8 Inch Our Architectural trim offers Colonial-style PVC Moulding, such as: Crown 6 inch colonial baseboard At 65-90 cents a linear foot. Joshua Zeichner, MD, explains, “The skin on your feet is subject to friction and trauma which can lead to barrier disruption, dryness, and inflammation.” Lavender Scented Pair 2.4 Fl Oz (Pack of 1) 45,416 2500 (10.42/Fl Oz)30.00 22. Foot Peel Mask,3Pcs Natural Aloe Vera Gel Foot Mask,Foot Peel Mask For Hard Skin,Exfoliating Feet Peeling Socks,Foot Callus Remover,Foot Care,Feet Hard Skin Remover,Pedicure Sets For Feet (Lavender) 1. Whether you’re going on daily walks or run at your local park everyday, our feet go through a lot. Foot Peel Mask - Baby Foot Original Exfoliant Foot Peel - Repair Rough Dry Cracked Feet and remove Dead Skin, Repair Heels and enjoy Baby Soft Smooth Feet 2.4 Fl. An affordable, effective, and doctor-recommended solution to dry, cracked heels: An at-home foot peel. So if your feet feel calloused, it's probably time you show them a little TLC. : ALIVER Foot Peel Mask 3 Pack, Exfoliator Peel Off Calluses Dead Skin Callus Remover, Baby Soft Smooth Touch Feet-Men Women (Lavender) : Beauty. Walking all day, climbing up and down stairs, and jumping around during workouts-your feet go through a lot. ![]() ![]() ![]() ![]() The PureSource 2 WF2CB is designed with a carbon-based filter to improve your water by removing the odor and taste of chlorine for smoother drinking, making it easy to keep the whole family hydrated.Designed to remove harmful contaminants giving you peace of mind with every glass Enjoy fresh tasting water right from the fridge and directly in your glass with the PureSource 2 water filter.With soft water, fewer minerals are being dissolved and, therefore, less likely to build up and cause discoloration: no more scum, problematic cuticles, and flaking skin. In addition to other beauty improvements, your nails can also improve. With this process, you won’t be as itchy or irritated, and your skin will be beautiful and clear. If you have sensitive skin or have skin affected by dry weather, then you should consider a water filtration system. With soft water, users will have fewer clogged pores, and skin will be less likely to dry out. Like the improvements to hair, users of water filtration systems can have better skin. Because hard minerals have been removed from the water, it is less damaging to hair follicles and can leave your hair feeling softer and healthier, leaving a healthier look. Most people realize that the benefit of water filtration is access to soft water, which is better for your beauty regimen. So, in addition to saving water while using soft water and not having to replace your appliance as often, a water softener can also save on detergent and other cleaning materials! 7. Using Less DetergentĪ study from Scientific Services found that using soft water or filtered water for washing machines can reduce detergent use up to 50% and save energy. Water Filtration systems are a one-time purchase, with the minimal cost of replacing a single water filter every year, saving you money in the long run. ![]() These other filtration systems cost more over time. For example, some households get bottled water or use Brita filters. When you need access to safe, clean water, water filtration is the most cost effective in the long term. Save your family the stress and money by installing a water filtration system before your appliances get worse for wear. It also costs you a lot more money to replace appliances damaged by hard water. With more minerals in your water, it’s likelier that you’ll spend more money on water due to the build-up issue. Save on Water Bill and Cost of Replacing Appliances By getting a water filtration system, you improve your appliance lifespan.Īccording to a study from 2009, water-softening filtration systems can extend the longevity of appliances by as much as 40%! A washing machine, for example, can last up to 11 years on soft water systems compared to 7.7 on hard water. Refrigerators, dishwashers, ice machines, hot water heater tanks, and washing machines will need replacing faster than usual when hard water is present. The mineral build-up, which you can see, tends to happen around the water entry points and cause issues with how the product functions. Limescale damage and soap scum build-up are the two big problems associated with hard water usage. Water Filtration systems remove harmful contaminants that harm your appliances and affect their longevity. Water softeners reduce maintenance for limescale and save your plumbing system. These minerals can also damage your plumbing system.īy installing a water filter, you’ll have cleaner pipes that are less likely to be damaged by minerals. These include lead, calcium, phosphate, arsenic, mercury, fluoride, chloride, cyanide, and ammonia. Water filtration removes harmful contaminants and minerals from your plumbing system.
![]() ![]() Typically, you’ll want to use the Wall Coin and drop it only when you’ve got at least ten coins. As the wall is just temporary, you should make the most out of the Wall Coin and only use it when you really need it. For a few seconds, this will bring up a wall on both sides of the platform, thus preventing coins and prizes from falling on the sides. Set amidst an ambiance of festivity, Carnival Coin Dozer is bound to enhance your experience of playing this arcade game. The Wall Coin is one of the special coins you’ll bump into in Coin Dozer. This will allow coins and prizes to fall on the slot, but you should only use the shaker if there are prizes or special coins that are especially near the slot. If your Shake Meter is full, you can use the Coin Shaker by tapping on the meter. Use The Coin ShakerĪny coins that drop on the side of your platform will not be added to your total coins rather, they’ll all go to the Coin Shaker on the right side of your display. Make sure you’re dropping the coins on the proper slot – dropping them on both the left and right side of the platform before pushing them in the middle would help you avoid the pitfall of dropping the prize on the side. These prizes come in four colors, and if you collect all of those colors, you’ll get a tidy bonus. Collect Prizes Of All Colors And Drop Coins On The SideĪs this is a mobile version of the coin dozer games at carnivals and fairs, you can collect several prizes you may have seen at those events – we’re talking bears, fish, sunglasses, and toy cars, to name a few. As a helpful hint, all coins that are dropped on the slots will go toward the number of coins you’re allowed to drop. That will also allow you to move the coins and prizes to the slot faster. Drop Three Coins Simultaneouslyĭropping one coin individually is fine, but what about dropping three coins all together at once? That would actually be a better strategy, as you’ll be landing them with more force as they drop onto the platform. And here’s how you can get more prizes – a list of Coin Dozer cheats, tips and tricks for you to check out. However, it’s not as easy as it all seems – you’ll want to avoid “(dozing) the prizes off the sides.” All in all, this is a game that boasts of stunning graphics, a good variety of puzzles to complete, and, as mentioned, tons of special coins and prizes. ![]() You have to drop gold coins onto the titular Coin Dozer, and as you do this you’ll be encountering some special coins. This title is described as the virtual version of the addictive arcade coin pusher you’ve spent hours playing at the carnival. Coin Dozer is a game you can play regardless whether you own an Android or iOS device. ![]() ![]() ![]() You might have seen the central elements – the fans, the glowing tubes, the weird machinery – in Doom 3, but it doesn’t mean they don’t look fabulous here.Īnd unlike Doom 3, the pacing is superb. Admittedly, their taste in interior design has not improved much (brown industrial is still THE look on Planet Strogg) but when the level designers really put their imaginations to work there’s some beautiful alien weirdness on display here. The Strogg were always a deeply unpleasant bunch, and they’ve only become more so with their new makeover: all the torn flesh, grotesque techno implanting and ghastly rending and tearing implements looks even less wholesome this time around. Let’s make no bones about it, this engine produces the most stunning indoor environments and lighting effects around, and lends itself to the most detailed horrific and macabre creatures you could hope for. ![]() In many respects, this is the game’s biggest selling point. For large chunks of the game you could simply be playing Quake II remixed with the Doom 3 engine. Raven has had the sense to steal some new elements from the likes of Halo and Call of Duty, but Quake 4 has neither the emergent, open gameplay of the former or the tough, squad-based dynamic of the latter. It’s really, really intense stuff, with enemies coming from all sides and even bursting through the scenery to get at you, and if it lets up for a few minutes here and there, it’s only to give you enough time for the next big shock. ![]() It follows on almost directly where iD’s classic left off, features a very similar weapon set and enemies that are clearly from the same gene pool, and has action modelled very clearly on the Quake II model. This is Quake II – a gung-ho science fiction war movie of a game – taken to the max. If Quake 4 didn’t look so damn cutting-edge, we’d have to label it a retro game and be done with it. But then it goes and fumbles the second part. It couldn’t be any more like Quake II if it had been designed by the exact same people immediately afterwards. The thing about iD and Raven’s Quake 4 is that it absolutely aces the first part. But at the same time, it has to take the series somewhere new – pull the characters and their story into new territories and new situations embrace new ideas and bigger themes. On the one hand, it has to be faithful to the original to have something of the old feel, a few old characters, and a few common threads to pull the two stories together. A sequel – whether it’s a movie, book or game – has two duties. ![]() ![]() Model 1 - Switches character to feminine body Debug/creative mode commands Valheim commands: Creative modeĪlso in singleplayer, you can enter debug mode to access a few more cheats and what is essentially a creative mode, where you can build without a workbench or resources.ī - Toggle for creative mode building, no workbench or resources needed. Model 0 - Switches character to masculine body Hair - Removes character's hair (permanently)īeard - Removes character's beard (permanently) Resetwind - Resets the wind angle and intensity Wind - Adjusts the direction and intensity of the wind. Removedrops - Removes all items dropped in the area. Save - Forces the game to save the current world state. Resetcharacter - Resets all of your character data.ĭpsdebug - Toggles dps debug print on and off. ![]() Raiseskill - Raises the named skill by the value entered. Goto Teleports player to the specified coordinates. Puke - Empties stomach of food and resets health and stamina.įfsmooth 1 - Adds smooth movements to free camera.įfsmooth 0 - Resets smooth movements to normal. To deactivate cheats, type devcommands and press enter again. Then you'll be able to use the following cheats in singleplayer mode. Type devcommands and press enter (previously, the command was 'imacheater' but that has changed). Once in the game, to activate cheats, open the console by pressing F5.
![]() Close to: Times-Union Center for the Performing Arts, Northbank Riverwalk.Close to: Federal Reserve Building, Interline Brands, Sally Corporation.Ticket Vending Machine available at ground level.Close to: Jacksonville Regional Transportation Center at LaVilla, Intercity Bus Terminal (Greyhound, Megabus, RedCoach), Prime Osborn Convention Center.Trains arrive every 8 minutes Stations DOWNTOWN LaVilla Station Please check our website and social media accounts for these special hours. The Skyway may also have extended hours for special events downtown, such as July 4th or New Year's Eve. For a monthly pass or information on our metered parking, call (904) 630-3100. The Skyway station at Kings Avenue offers inexpensive Park-n-Ride facilities for commuters and visitors. Since JTA’s buses connect to the Skyway, passengers have complete flexibility to travel beyond Downtown to virtually anywhere JTA travels. In keeping with JTA’s original people mover plan, convenient Park-n-Ride lots are located near the Jefferson and Kings Avenue stations enabling employees, residents and visitors to leave their vehicles on the periphery of the Downtown area and travel in and out of the core without the hassles of traffic or parking. In addition to electronic message boards with real-time arrival and departure times, all Skyway stations are monitored by closed-circuit television and fully equipped with two-way voice communication and video cameras. Traveling via the Skyway is comfortable and efficient with quiet, climate-controlled, non-polluting vehicles departing stations at four-minute intervals during peak hours and at eight-minute intervals during off-peak hours. The fully automated Skyway features eight stations - five on the Downtown Northbank and three on the Southbank - providing convenient access to business, government, restaurants, shops, museums and entertainment venues. ![]() Johns River to Kings Avenue on the Southbank. The JTA Skyway is a 2.5-mile long, elevated monorail system that glides high above the busy streets of Downtown Jacksonville, crossing the St. ![]() ![]() ![]() Since the gel and membrane are sandwiched tightly during the procedure, the proteins maintain the separation they achieved during the SDS-PAGE electrophoresis. (In wet transfer systems, there is a sponge on either side of the sandwich.) The negatively charged proteins in the gel are pulled in an electric current toward a the positively charged anode and into the membrane. A “transfer sandwich” of filter paper – gel – membrane – filter paper is placed between two electrodes. Most scientists use an electric current to transfer their proteins from gels to membrane. For most proteins, the 0.45 μm size works well, but for lower MW proteins, you should consider 0.2 μm. Membranes are available in different pore sizes, most commonly 0.2 μm and 0.45 μm. The size of the pore determines the size of the protein that can bind without passing through. The pore size of the membrane is also important. PVDF has a higher binding capacity and is stronger but needs to be activated with methanol and is more expensive.Ĭlick on my full-length article for a more in-depth comparison of these two membranes. Nitrocellulose is cheaper and has lower background but is fragile and has a lower binding capacity than PVDF. Targeted therapy is a kind of gene product specifically expressed by tumor cells as a therapeutic target. Studies have found that aquaporin 4 can be used as a target for targeted therapy of lung cancer. Both membranes are microporous substrates that bind proteins to their surface through hydrophobic interactions. As a technique widely used in protein detection and analysis, Western blot analysis can detect protein expression levels in cells or extracts. Nitrocellulose and PVDF (polyvinylidene difluoride) are the membranes of choice for most Western blotting applications. The biggest advantages to transferring to a membrane are that membranes are easier to handle than gels and they allow for easier detection by getting the proteins out of the gel onto a thinner substrate. Transferring to a membrane makes antibody detection easier, but you need to consider which membrane to choose. This step involves incubating the transfer membrane in a solution containing an antibody to the protein of interest, and using a fluorescent tagged secondary antibody for visualization.Getting the separated proteins out of the gel and bound to a membrane allows for easier detection. ![]() Separation of the proteins in your lysate by molecular weight is done through electrophoresis. Read our lysate preparation protocol here. You can read about our recommended lysis buffer here. To be successful, you must get your proteins out of your tissue or cells. There are 4 basic steps in the Western Blot procedure. It was the third technique developed in membrane transfer, after “Southern blotting” (for DNA) and “Northern blotting” (for RNA). It was introduced in 1979 by Harry Towbin’s research lab in Switzerland. The Western Blot (or immunoblot) technique uses antibodies to detect protein targets that have been bound to a membrane. Western Blotting is a protein detection technique. Read my full-length piece in our website’s Education section. Regardless of whether you perform Western blots frequently in your lab or are new to the technique, here is a reminder of (or an intro to) the fundamentals behind the box. ![]() |